Guideline 1 – Screening, diagnostic assessment, risk assessment, life-stage and adolescents

||Guideline 1 – Screening, diagnostic assessment, risk assessment, life-stage and adolescents
Guideline 1 – Screening, diagnostic assessment, risk assessment, life-stage and adolescents2017-11-15T16:47:55+00:00

Guideline 1 – Screening, diagnostic assessment, risk assessment, life-stage and adolescents

The clinical questions being addressed:

  • At what time point after onset of menarche do irregular cycles indicate ongoing menstrual dysfunction related to PCOS?
  • In women with suspected PCOS, what is the most effective measure to diagnose PCOS-related hyperandrogenism (biochemical)?
  • In women with suspected PCOS, what is the most effective measure to diagnose PCOS-related hyperandrogenism (clinical)?
  • What is the most effective ultrasound criteria to diagnose PCOS?
  • Is AMH effective for diagnosis of PCOS?
  • Is AMH effective to diagnosis of PCOM?
  • What is the post-menopausal phenotype of PCOS?
  • Are women with PCOS at increased risk for cardiovascular disease (CVD)?
  • In women with PCOS, what is the most effective tool/method to assess risk of cardiovascular disease (CVD)?
  • Are women with PCOS at increased risk for impaired glucose tolerance, gestational diabetes and type 2 diabetes mellitus?
  • In women with PCOS, what is the most effective tool/method to assess risk of type 2 diabetes mellitus?
  • Are women with PCOS at increased risk for sleep apnea?
  • What is the method/tool most effective to screen for sleep apnea in PCOS?
  • What is the risk of PCOS in relatives of women with PCOS and should they be screened?
  • What is the disease risk in relatives of PCOS (CVD, T2DM)?
  • If time permits: Are all three criteria required to diagnose PCOS in adolescents?

Members of GDG 1


Professor Joop Laven (Chair)
Obstetrician-Gynaecologist
Erasmus MC Rotterdam


Professor Robert Norman (Deputy Chair)
Obstetrician-Gynaecologist, Reproductive endocrinologist, chemical pathology
University of Adelaide


Professor Marianne Andersen
Endocrinologist
University of Copenhagen


Professor Ricardo Azziz
Obstetrician/Gynaecologist, Reproductive Endocrinologist.
Georgia Regents University


Dr Preeti Dabadghao
Paediatric endocrinologist
Sanjay Gandhi Postgraduate Institute of Medical Sciences


Professor Didier Dewailly
Endocrinologist/ultrasound
University of Lille 2


Professor Stephen Franks
Endocrinologist
Imperial College London


Dr Kathleen Hoeger
Obstetrician/Gynaecologist, Reproductive Endocrinologist
University of Rochester Medical Centre


Dr Samantha Hutchison
Endocrinologist
Monash Health


Professor Ernest Ng
Reproductive Endocrinologist, Obstetrician-Gynaecologist
The University of Hong Kong


Professor Sharon Oberfield
Paediatric endocrinologist
Columbia University, Department of Paediatrics


Dr Jane Woolcock
Obstetrician-Gynaecologist, Obstetric Ultrasound,
Pelvic Pain SA